Role of Iron Metabolism in Breast Cancer Patients

Authors

  • Rakesh Dhankhar Professor, Department of Radiotherapy, Pt. B.D.S. PGIMS, Rohtak, Haryana, India
  • Adarsh C Ex-resident, Department of Radiotherapy, Pt. B.D.S. PGIMS, Rohtak, Haryana, India
  • Kiran Dahiya Professor, Department of Biochemistry, Pt. B.D.S. PGIMS, Rohtak, Haryana, India
  • Veena Singh Ghalaut Senior Professor and Head, Department of Biochemistry, Pt. B.D.S. PGIMS, Rohtak, Haryana, India
  • Nityasha Professor, Department of Surgery, Pt. B.D.S. PGIMS, Rohtak, Haryana, India
  • Anil Kumar Dhull Medical Officer, Department of Radiotherapy, Pt. B.D.S. PGIMS, Rohtak, Haryana, India
  • Anil Khurana Medical Officer, Department of Radiotherapy, Pt. B.D.S. PGIMS, Rohtak, Haryana, India

DOI:

https://doi.org/10.18488/journal.95/2014.1.2/95.2.45.51

Abstract

Iron metabolism is closely related to carcinogenesis. In this study, iron, ferritin and TIBC were analysed in 30 patients of early stage, 30 of advanced stage breast carcinoma before and after treatment and the results were compared with 30 healthy controls. The levels of all the three parameters were found to be significantly higher in breast cancer patients as compared to healthy controls and patients with advanced disease showed greater values as compared to early stage disease. These levels decreased after treatment and the difference was more significant in patients with complete response. Serum analyses of iron, ferritin and TIBC may help in assessing the severity and prognosis of the disease.

Keywords:

Breast cancer severity, Iron, Ferritin, TIBC, Hormone-associated cancer, Effect of treatment

Abstract Video

Published

2014-12-15

How to Cite

Dhankhar, R. ., C, A. ., Dahiya, K. ., Ghalaut, V. S. ., Nityasha, Dhull, A. K. ., & Khurana, A. . (2014). Role of Iron Metabolism in Breast Cancer Patients. Cancers Review, 1(2), 45–51. https://doi.org/10.18488/journal.95/2014.1.2/95.2.45.51

Issue

Vol. 1 No. 2 (2014)

Section

Articles