Study of antibiotic susceptibility of uropathogenic germs and epidemiology in patients at the Ignace Deen National Hospital in Conakry (Republic of Guinea)

Abstract

Out of 228 urines analysed, the prevalence was 85%. Married people are the most exposed, with 78%. Households (30%), administrative staff (19%) and patients from the commune of Kaloum (35%) were the most represented. 58% were male, with a sex ratio (male/female) of 0.73. The 51 and over age group was the most affected with 32%, followed by the 21-30 age group with 19% and the 31-40 age group with 16%. The age groups least represented were 11-20 and 0-10 with 5% and 6% respectively. Married people are the most affected, with 82%, compared with 18% of single people. The married/single ratio is 4.5. Housewives are the most represented with 15%, followed by sales staff with 18% and pupils/students with 13%. Patients from the Urology department accounted for 45%, followed by Gynaecology with 21%, Rheumatology with 12%, and patients from elsewhere accounted for 10%. Patients from the commune of Kaloum were the most represented with 36%, followed by patients from outside Conakry with 20% and Matam with 19%. 61% of the urine was clear, 33% turbid and 6% haematic. 15% of urine was germ-free, 63% contained gram-negative bacilli and 37% gram-positive cocci. Leukocyturia was significant in 86% of cases. Epithelial cells were present in 6%, haematuria in 3%, yeast in 3% and oxalate crystals in 2%. The germ Escherichia coli was the most incriminated in 40% followed by Staphyloccus aureus with 32%, Klebsiella pneumoniae with 8%, Pseudomonas aeruginosae with 5%, Acinetobacter baumannii with 3% and Staphylococcus haemolyticus with 2% and the other germs were 1%. Antibiotics such as amikacin were effective in 63%, Nitrofurantoine in 79% and Imipenem in 76%.